Open calls · Research grant · Medicine
Somatic Mosaicism across Human Tissues (SMaHT) Program: Experimental and Computational Technology Development (RM1 Clinical Trial Not Allowed)
National Institutes of Health · Trans-NIH Research Support · RFA-RM-28-017
Deadlines
- 1 Jul 2027 Estimated deadline in 231 days
Who can apply
- Where the work is done
- United States
- Who applies
- An organisation
About the call
The purpose of the Somatic Mosaicism across Human Tissues (SMaHT) Network is to advance discovery of biological processes and disease mechanisms mediated by somatic mutations in human tissues. Since 2023, the program has generated multi-omic somatic mutation datasets from standardized human tissues spanning all three germ layers. Building on the Stage 1 foundation, the NIH intends to issue a Notice of Funding Opportunity (NOFO)supporting Stage 2 of the SMaHT Experimental and Computational Technology Development initiative. The Experimental and Computational Technology Development initiative supports multidisciplinary development, optimization, validation, benchmarking, and dissemination of rigorous, cost-effective technologies for somatic mutation detection and functional interpretation.
Awardees will collaborate with other SMaHT Stage 2 initiatives to incorporate validated technologies into production workflows, pipelines, data releases, and community resources.
Text from the funder (US federal government, public domain).
Conditions in full
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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