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Open calls · Research grant · Pharmacology, Toxicology and Pharmaceutics

Effective and evidence-based responses to the increased availability and use of synthetic drugs and stimulants in Europe

European Commission · Horizon Europe · HORIZON-CL3-2027-01-FCT-05

Go to the funder’s page
Opens5 May 2027

Deadlines

  • 4 Nov 2027 Deadline in 358 days

Time of day: 17:00 Brussels time.

Who can apply

Countries
Applicants from any country can take part. Funding is usually limited to the EU, associated countries and listed low- and middle-income countries; sanctions apply to some.
Who applies
A consortium of organisations

Money

Per project
up to €4M per project
Total budget
€8M
Expected awards
2

About the call

Expected Outcome:
Project results are expected to contribute to all of the following expected outcomes:

• Evidence base is improved for effective prevention, treatment and harm reduction of synthetic drugs and stimulants in Europe;

• Relevant European security practitioners, notably Police Authorities, Civil Society Organisations and Non-Governmental Organisations, are equipped with skills, tools and technology aimed at reducing the violence and offences associated with use and marketing of these substances, as well as at combatting drug trafficking from its origin to destination (i.e., through the entire supply chain);

• Increased understanding of relevant European security practitioners and policymakers regarding the influence of external drivers of change of societal, technological, legal, economic and ethical nature to the availability and use of different types of synthetic drugs and drug markets.
Scope:
This topic asks for proposals that seek to develop effective and evidence-based responses to the growing prevalence of synthetic drugs and stimulants, such as cocaine and crack cocaine, within the EU. As these substances increasingly influence the drug landscape, the urgent need for enhanced understanding and strategies in their prevention, treatment, and harm reduction has never been clearer. Amongst other, there is also a lack of pharmacological data for the emerging drugs, needed to do proper risk assessments and interventions of these drugs in Europe. Key focus areas include:

• Evidence-based approaches, strengthening the evidence base to inform effective prevention strategies, treatment modalities, and harm reduction practices targeted at synthetic drugs and stimulants. This includes identifying best practices in current interventions and evaluating their efficacy.

• Reducing violence and offending exploring strategies to mitigate the violence and criminal behaviour associated with the use and marketing of synthetic drugs. This involves understanding the socio-economic and cultural factors, including the gender, age, or other social factors, that contribute to these phenomena and proposing targeted interventions.

• Improving technologies and tools to combat drug trafficking from its origin to destination (i.e., through the entire supply chain).

• External drivers of change, analysing the impact of geopolitical situations, legal frameworks, and societal factors on the availability and consumption of various drugs, and addressing how international crises affect organised crime and drug markets in the EU. This includes investigating the repercussions of global developments on local drug dynamics and identifying adaptive response strategies.
In light of the underdeveloped evidence base surrounding synthetic drugs, proposals should aim to foster collaboration among researchers, policymakers, and security practitioners to create a comprehensive and effective response to this pressing issue in Europe, previous research, including but not limited to research by other Framework Programmes’ projects. Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. To ensure the active involvement of and timely feedback from relevant security practitioners, proposals should plan a mid-term deliverable consisting in the assessment of the project’s mid-term outcomes, performed by the practitioners involved in the project.
Activities proposed within this topic should address, in a balanced way, both technological and societal dimensions of the issue under consideration. The proposals funded under this topic are expected to engage with the Europol Innovation Lab during the lifetime of the project, including validating the outcomes, with the aim of facilitating future uptake of innovations for the law enforcement community. Similarly, the proposals funded under this topic are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes. Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.
Technology Readiness Level - Technology readiness level expected from completed projects
Activities are expected to achieve TRL 6-8 by the end of the project – see General Annex B.

Text from the funder (European Commission, CC BY 4.0).

Conditions in full

"> General conditions
1. Admissibility Conditions: Proposal page limit and layout
described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.
Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.
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2. Eligible Countries
described in Annex B of the Work Programme General Annexes.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide .

3. Other Eligible Conditions
The following additional eligibility criteria apply:
This topic requires the active involvement, as beneficiaries, of at least 3 Police Authorities[[In the context of this Destination, ‘Police Authorities’ means public authorities explicitly designated by national law, or other entities legally mandated by the competent national authority, for the prevention, detection and/or investigation of terrorist offences or other criminal offences, specifically excluding police academies, forensic institutes, training facilities as well as border and customs authorities.]] and at least 2 Civil Society Organisations (or Non-Governmental Organisations) from at least 3 different EU Member States or Associated Countries. For these participants, applicants must fill in the table “Information about security practitioners” in the application form with all the requested information, following the template provided in the submission IT tool.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

described in Annex B of the Work Programme General Annexes.

4. Financial and operational capacity and exclusion
described in Annex C of the Work Programme General Annexes.

5a. Evaluation and award: Award criteria, scoring and thresholds
are described in Annex D of the Work Programme General Annexes.

5b. Evaluation and award: Submission and evaluation processes
are described in Annex F of the Work Programme General Annexes and the Online Manual .

5c. Evaluation and award: Indicative timeline for evaluation and grant agreement
described in Annex F of the Work Programme General Annexes.

6. Legal and financial set-up of the grants
The granting authority may, up to 4 years after the end of the action, object to a transfer of ownership or to the exclusive licensing of results, as set out in the specific provision of Annex 5.

Eligible costs will take the form of a lump sum as defined in the Decision of 7 July 2021 authorising the use of lump sum contributions under the Horizon Europe Programme – the Framework Programme for Research and Innovation (2021-2027) – and in actions under the Research and Training Programme of the European Atomic Energy Community (2021-2025) [[This decision is available on the Funding and Tenders Portal, in the reference documents section for Horizon Europe, under ‘Simplified costs decisions’ or through this link: https://ec.europa.eu/info/funding-tenders/opportunities/docs/2021-2027/horizon/guidance/ls-decision_he_en.pdf ]].

described in Annex G of the Work Programme General Annexes.

Specific conditions
described in the [specific topic of the Work Programme]

Some activities resulting from this topic may involve using classified background and/or producing of security sensitive results (EUCI and SEN). Please refer to the related provisions in section B Security — EU classified and sensitive information of the General Annexes.

Application and evaluation forms and model grant agreement (MGA):
Application…

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