- Grants since 2016
- 484
- Awarded, last 5 years (where amounts are published)
- 57M
- Funded works, last 5 years
- 437
- Funded works, all time
- 2 006
Grants
2017–2018 · award
Enzymatic regulation of toxic G-quadruplex structures in ALS cells by G4 resolvase 1
Philip Smaldino
2017–2021 · award
Molecular basis and effects of Ubiquilin-2 phase separation on association with ALS-linked proteins
Carlos Castañeda
2017–2021 · award
Enhancing Mask/ANKHD1 activity as a therapeutic approach for treating ALS
Chunlai Wu
2017–2018 · award
Determining whether gain of toxicity from ALS/FTD-linked hexanucleotide repeat expansion synergizes with reduced C9ORF72 function to drive age-dependent ALS/FTD
Qiang Zhu
2017–2018 · award
Neuro collaborative
Don Cleveland
2017–2020 · award
Understanding the role of dynamic polymerization of TDP-43 in health and disease
Magdalini Polymenidou
2017 · award
Rad is an agent of muscle atrophy and neuromuscular junction decline
Roger Bannister
2017–2018 · award
Developing a mouse model to study the cell-type specific effects on ALS disease spread
Jacob Ayers
2016–2018 · award
Nutrition and disease prevention: examining polyunsaturated fats and risk of ALS
Alberto Ascherio
2016–2017 · award
Enhancing Mask activity as a therapeutic approach for treating ALS
Chunlai Wu
2016–2017 · award
Targeting the unfolded protein response in mutant SOD1 induced ALS
Raymond Roos
2016–2018 · award
ALS One - Mapp ALS (Massachusetts ALS Partnership)
Nazem Atassi
2016–2017 · award
The immune system underlies Amyotrophic Lateral Sclerosis
Benjamin Murdock
2016–2018 · award
Modeling selective vulnerability and disease specific functions in mice by the comparison of C9orf72 repeat models to a novel disease control
Tiffany Todd
2016–2020 · award
Postmortem MRI and pathology in ALS patients to identify biomarkers and evidence of oligodendrocyte dysfunction
Bruce D. Trapp
2016–2021 · award
Preclinical investigation of CuATSM in mice and dogs
Joseph Beckman
2016–2018 · award
Silencing mutant SOD1 and C9orf72 in vivo using innovative hydrophobic siRNA scaffolds: a novel therapeutic path for the treatment of ALS
Bruno Miguel Da Cruz
2016–2018 · award
Impact of combined inspiratory/expiratory respiratory training in ALS
Emily Plowman
2016–2018 · award
Prospective validation of ALS disease models and tools
David Ennist
2016–2019 · award
Amylyx Pharmaceuticals, Inc.
Joshua Cohen
2016–2020 · award
ALS One - Mapp ALS (Massachusetts ALS Partnership)
Robert Brown
2016–2017 · award
Treatment of ALS by targeted delivery of GDNF to motoneurons using novel V-SmartTM nanovesicles
Eliahu Heldman
2016–2020 · award
NeuroBANK as an accelerated clinical research environment: development, CORE services to ALS research community
Alexander Sherman
2016–2019 · award
Development of small-molecule activators of glutamate transporter EAAT2 for ALS
Chien-Liang Lin
2016–2017 · award
ALS ONE
Steven Perrin
2016–2017 · award
Development of microglia-targeted MRI/PET traceable nanovectors as innovative theranostic platform for investigating and shaping microglia reactivity to improve ALS therapy
Marco Peviani
2016–2018 · award
Clinically-useful brain-machine interface control of a robotic prosthetic arm by people with ALS
Sergey Stavisky
2016–2018 · award
Development and characterization of novel mouse models of ALS
John Landers
2016–2017 · award
Establishing uniform methods of data collection in Epic ALS Centers
Robert Miller
2016–2018 · award
Comprehensive analysis of RNA localization and transport mechanisms in wildtype and ALS motor neurons
Gene Yeo
2016–2018 · award
Project MinE US-Whole Genome sequencing of a large cohort of sporadic ALS Patients supplement No. 1 award to 235
John Landers
2016–2021 · award
NeuroLINCS DSGC
Christine Swanson-Fischer
2016–2018 · award
Validating inhibition of IRE1alpha kinase/RNase as a therapeutic approach to ALS
Richard Keenan
2016 · award
A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of NP001 in Subjects with Amyotrophic Lateral Sclerosis (ALS)
Robert Miller
2016–2017 · award
Reducing repeat toxicity as a therapeutic approach in C9ORF72 ALS/FTD
Mai El Mallah
2016–2019 · award
Pharmacodynamic biomarker development for C9ORF72 antisense therapy
Lindsey Hayes
2016–2019 · award
New mouse models to dissect out the function of the ALS-associated protein Matrin
Jada Lewis
2016–2020 · award
Molecular mechanisms of PABPN1-mediated suppression of TDP-43 toxicity
Wilfried Rossoll
2016–2019 · award
Project MinE US-Whole Genome sequencing of a large cohort of sporadic ALS Patients
John Landers
2016–2018 · award
Defining and addressing the complex needs of ALS caregivers
Orla Hardiman