Non-profit · founded 1990

Discovery Institute

Seattle, United States · discovery.org

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Citations, last 5 years: 139
Works, last 5 years: 72
h-index: 40
Scientists listed: 12
Grants since 2016: 829

Grants received

2018–2023 · research · R01

Novel roles for the Alzheimer's Disease (AD) risk gene, SORLA in neuroprotection in AD

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$682.3k

2018–2023 · training · T32

Frontiers in Fundamental and Translational Immunology

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$149.3k

2018–2020 · research · R21

Phage Display Detection of Alzheimer's Disease Markers

Erkki Ruoslahti · Discovery Institute · funded by National Institutes of Health

$292.5kAlzheimer's disease research and treatments

2018–2023 · research · R01

Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation

Victoria Alison Blaho · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2018–2023 · training · T32

Frontiers in Fundamental and Translational Immunology

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$204.7k

2018–2020 · research · R21

Phage Display Detection of Alzheimer's Disease Markers

Erkki Ruoslahti · Discovery Institute · funded by National Institutes of Health

$243.8kAlzheimer's disease research and treatments

2018–2023 · training · T32

Frontiers in Fundamental and Translational Immunology

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$220.8k

2018–2023 · research · R01

Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation

Victoria Alison Blaho · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2018–2024 · research · R01

Novel roles for the Alzheimer's Disease (AD) risk gene, SORLA in neuroprotection in AD

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$681.3k

2018–2020 · research · R21

Transcriptional Regulation of Autophagy in Promoting Proteostasis Upon Hormetic Stress

Caroline Kumsta · Discovery Institute · funded by National Institutes of Health

$292.5kAutophagy in Disease and Therapy

2018–2023 · research · R01

Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation

Victoria Alison Blaho · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2018–2022 · research · R01

Inhibiting Multi-Functional ALDOA for Cancer Therapy

Garth Powis · Discovery Institute · funded by National Institutes of Health

$612.8k

2018–2022 · research · R01

Early development of small molecule dendritic cell immunopotentiators for the treatment of solid tumors

Sumit K Chanda · Discovery Institute · funded by National Institutes of Health

$737.9kVirus-based gene therapy research

2018–2024 · training · T32

Cancer Targets and Drug Discovery

Nicholas David Cosford · Discovery Institute · funded by National Institutes of Health

$246.6k

2018–2020 · research · R21

A role for TREM2/Abeta interactions in microglia-regulated AD pathogenesis

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$292.5kNeuroinflammation and Neurodegeneration Mechanisms

2018–2023 · program · P01

An automated pipeline for macromolecular structure discovery in cellular electron cryo-tomography

Niels Volkmann · Discovery Institute · funded by National Institutes of Health

$981.6kAdvanced Electron Microscopy Techniques and Applications

2018–2024 · research · R01

S1P signaling machinery in neuroimmune interactions

Yasuyuki Kihara · Discovery Institute · funded by National Institutes of Health

$426.6kSphingolipid Metabolism and Signaling

2018–2022 · research · R01

Inhibiting Multi-Functional ALDOA for Cancer Therapy

Garth Powis · Discovery Institute · funded by National Institutes of Health

$655.6k

2018–2020 · program · P01

An automated pipeline for macromolecular structure discovery in cellular electron cryo-tomography

Niels Volkmann · Discovery Institute · funded by National Institutes of Health

$928.4k

2018–2020 · research · R21

Transcriptional Regulation of Autophagy in Promoting Proteostasis Upon Hormetic Stress

Caroline Kumsta · Discovery Institute · funded by National Institutes of Health

$243.8kAutophagy in Disease and Therapy

2018–2021 · research · R01

Early development of small molecule dendritic cell immunopotentiators for the treatment of solid tumors

Sumit K Chanda · Discovery Institute · funded by National Institutes of Health

$371kVirus-based gene therapy research

2018–2020 · research · R21

A role for TREM2/Abeta interactions in microglia-regulated AD pathogenesis

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$243.8kNeuroinflammation and Neurodegeneration Mechanisms

2018–2023 · research · R01

Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation

Victoria Alison Blaho · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2018–2021 · career development · K22

A pan-cancer role for MutL loss in inducing treatment resistance

Svasti Haricharan · Discovery Institute · funded by National Institutes of Health

$147.2kGenetic factors in colorectal cancer

2018–2021 · career development · K22

A pan-cancer role for MutL loss in inducing treatment resistance

Svasti Haricharan · Discovery Institute · funded by National Institutes of Health

$147.2kGenetic factors in colorectal cancer

2018–2023 · research · R01

Novel roles for the Alzheimer's Disease (AD) risk gene, SORLA in neuroprotection in AD

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$682.4k

2018–2023 · research · R01

Mechanisms of hematopoietic acute radiation syndrome induction and radioprotection through sphingosine 1-phosphate receptor 1 signal modulation

Victoria Alison Blaho · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2018–2023 · training · T32

Cancer Targets and Drug Discovery

Garth Powis · Discovery Institute · funded by National Institutes of Health

$240.6k

2018–2023 · training · T32

Frontiers in Fundamental and Translational Immunology

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$189.3k

2018–2019 · research · R03

Intrinsic and extrinsic regulation of antiviral T cell responses by MMP2

Bas Baaten · Discovery Institute · funded by National Institutes of Health

$97.5k

2018–2023 · research · R01

S1P signaling machinery in neuroimmune interactions

Yasuyuki Kihara · Discovery Institute · funded by National Institutes of Health

$426.6kSphingolipid Metabolism and Signaling

2018–2020 · research · R03

Intrinsic and extrinsic regulation of antiviral T cell responses by MMP2

Carl F Ware · Discovery Institute · funded by National Institutes of Health

$97.5k

2018–2023 · research · R01

S1P signaling machinery in neuroimmune interactions

Yasuyuki Kihara · Discovery Institute · funded by National Institutes of Health

$426.6kSphingolipid Metabolism and Signaling

2017–2022 · research · R01

Linking the microbiome and immune-checkpoint in melanoma by RNF5

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$603.6kCancer Immunotherapy and Biomarkers

2017–2022 · research · R01

Innate Immune Surveillance of HIV-1 During Transmission and Systemic Infection

Sumit K Chanda · Discovery Institute · funded by National Institutes of Health

$860.9kHIV Research and Treatment

2017–2021 · research · R01

Mechanism of ER Protein Misfolding-Induced Mitochondrial Dysfunction

Randal J. Kaufman · Discovery Institute · funded by National Institutes of Health

$614.4kMitochondrial Function and Pathology

2017–2021 · research · R01

alpha-Catenin/F-actin Structure at Cell-Cell Junctions

Dorit Hanein · Discovery Institute · funded by National Institutes of Health

$640.3k

2017–2020 · cooperative agreement · U01

Preclinical studies for the development of selective mGlu2 positive allosteric modulators to treat substance use disorders

Nicholas David Cosford · Discovery Institute · funded by National Institutes of Health

$3.8M

2017–2022 · research · R01

Innate Immune Surveillance of HIV-1 During Transmission and Systemic Infection

Sumit K Chanda · Discovery Institute · funded by National Institutes of Health

$563.1kHIV Research and Treatment

2017–2019 · fellowship · F32

Exploring the role of Fbxw7 in regulating satellite cell function and skeletal muscle regeneration

Michael John Stec · Discovery Institute · funded by National Institutes of Health

$49.4kMuscle Physiology and Disorders