Non-profit · founded 1990

Discovery Institute

Seattle, United States · discovery.org

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Citations, last 5 years: 139
Works, last 5 years: 72
h-index: 40
Scientists listed: 12
Grants since 2016: 829

Grants received

2021–2026 · research · R01

Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease

Jamey Marth · Discovery Institute · funded by National Institutes of Health

$487.5kGlycosylation and Glycoproteins Research

2021–2023 · research · R03

Targeting Checkpoint Inhibition in Anti-Tumor Responses

Linda Mac Pherson Bradley · Discovery Institute · funded by National Institutes of Health

$97.5kCancer Immunotherapy and Biomarkers

2021–2023 · research · R21

Targeting the VHR phosphatase for the treatment of sepsis in COVID-19 patients

Lutz Tautz · Discovery Institute · funded by National Institutes of Health

$292.5kProtein Tyrosine Phosphatases

2021–2026 · research · R01

Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$393.4kTelomeres, Telomerase, and Senescence

2021–2026 · research · R01

Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal Adenocarcinoma

Cosimo Commisso · Discovery Institute · funded by National Institutes of Health

$580.9k

2021–2026 · research · R01

Targeting the FBXO44/SUV39H1 Pathway in Cancer

Charles H. Spruck · Discovery Institute · funded by National Institutes of Health

$423.8k

2021–2025 · research · R01

Retinoic acid target genes and transcriptional mechanisms during eye development

Gregg L Duester · Discovery Institute · funded by National Institutes of Health

$378.3kRetinoids in leukemia and cellular processes

2021–2025 · research · R01

Retinoic acid target genes and transcriptional mechanisms during eye development

Gregg L Duester · Discovery Institute · funded by National Institutes of Health

$390kRetinoids in leukemia and cellular processes

2021–2023 · research · R21

Characterizing a potential role for TREM2 in modulating tau pathogenesis in response to Abeta

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$292.5kNeuroinflammation and Neurodegeneration Mechanisms

2021–2025 · research · R01

Discovery of small molecule regulators of atrial cardiomyocyte action potential duration to restore normal cardiac rhythm in atrial fibrillation

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$487.5kAtrial Fibrillation Management and Outcomes

2021–2023 · research · R21

Targeting the VHR phosphatase for the treatment of sepsis in COVID-19 patients

Lutz Tautz · Discovery Institute · funded by National Institutes of Health

$243.8kProtein Tyrosine Phosphatases

2021–2026 · research · R01

Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$428.5kTelomeres, Telomerase, and Senescence

2021–2026 · research · R01

Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$628.6kTelomeres, Telomerase, and Senescence

2021–2025 · research · R01

Discovery of small molecule regulators of atrial cardiomyocyte action potential duration to restore normal cardiac rhythm in atrial fibrillation

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$487.5kAtrial Fibrillation Management and Outcomes

2021–2023 · research · R21

Multi-strain, live biotherapeutics as adjuncts to checkpoint inhibitor therapy

Hyungsoo Kim · Discovery Institute · funded by National Institutes of Health

$263.1kCancer Research and Treatments

2021–2026 · research · R01

Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal Adenocarcinoma

Cosimo Commisso · Discovery Institute · funded by National Institutes of Health

$574.1k

2021–2026 · program · P01

Aging as a Risk Factor and Target for Prevention of Liver Cancer

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$2.5M

2021–2024 · fellowship · F32

Identifying novel networks of candidate Atrial Fibrillation genes in the Drosophila cardiac aging model

James Kezos · Discovery Institute · funded by National Institutes of Health

$71.7k

2021–2026 · research · R01

Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cells

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$600.5k

2021–2023 · research · R21

Characterizing a potential role for TREM2 in modulating tau pathogenesis in response to Abeta

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$243.8kNeuroinflammation and Neurodegeneration Mechanisms

2021–2026 · research · R01

Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cells

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$676.1k

2021–2023 · research · R56

New Down syndrome brain organization revealed by single-cell genomics

Jerold Chun · Discovery Institute · funded by National Institutes of Health

$1.4MDown syndrome and intellectual disability research

2021–2025 · research · R01

Discovery of Glutaryl-CoA Dehydrogenase inhibitors for melanoma and pancreatic cancer

Eduard A. Sergienko · Discovery Institute · funded by National Institutes of Health

$577.2k

2021–2026 · research · R01

Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal Adenocarcinoma

Cosimo Commisso · Discovery Institute · funded by National Institutes of Health

$574.1k

2021–2022 · research · R35

Identifying and Targeting the Drivers of Pediatric Brain Tumors

Robert J. Wechsler-Reya · Discovery Institute · funded by National Institutes of Health

$682.5kGlioma Diagnosis and Treatment

2021–2026 · research · R01

Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal Adenocarcinoma

Cosimo Commisso · Discovery Institute · funded by National Institutes of Health

$556.5k

2021–2026 · research · R01

Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease

Jamey Marth · Discovery Institute · funded by National Institutes of Health

$487.5kGlycosylation and Glycoproteins Research

2021–2026 · research · R01

Targeting the FBXO44/SUV39H1 Pathway in Cancer

Charles H. Spruck · Discovery Institute · funded by National Institutes of Health

$437.1k

2021–2026 · research · R01

Retinoic acid target genes and transcriptional mechanisms during eye development

Gregg L Duester · Discovery Institute · funded by National Institutes of Health

$390kRetinoids in leukemia and cellular processes

2021–2022 · grant · S10

Digital Spatial Profiler Analysis Instrument

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$302.5kSingle-cell and spatial transcriptomics

2021–2026 · research · R01

Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$393.4kTelomeres, Telomerase, and Senescence

2021–2026 · program · P01

Aging as a Risk Factor and Target for Prevention of Liver Cancer

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$2.6M

2021–2026 · program · P01

Aging as a Risk Factor and Target for Prevention of Liver Cancer

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$2.6M

2021–2024 · research · R56

New Down syndrome brain organization revealed by single-cell genomics

Jerold Chun · Discovery Institute · funded by National Institutes of Health

$1.4MDown syndrome and intellectual disability research

2021–2026 · research · R01

Regulation and Function of Stromal Macropinocytosis in Pancreatic Ductal Adenocarcinoma

Cosimo Commisso · Discovery Institute · funded by National Institutes of Health

$585.8k

2021–2026 · research · R01

Targeting the FBXO44/SUV39H1 Pathway in Cancer

Charles H. Spruck · Discovery Institute · funded by National Institutes of Health

$446.1k

2021–2026 · research · R01

Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease

Jamey Marth · Discovery Institute · funded by National Institutes of Health

$472.9k

2021–2027 · program · P01

Aging as a Risk Factor and Target for Prevention of Liver Cancer

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$2.5M

2021–2027 · research · R01

Cytoplasmic chromatin fragments in cell senescence - novel mechanisms and interventions

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$419.9k

2021–2027 · research · R01

Mechanisms that couple irregular development of fetal melanoblasts to premature exhaustion of adult melanocyte stem cells

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$619.8k