Non-profit · founded 1990

Discovery Institute

Seattle, United States · discovery.org

Manage this page

Citations, last 5 years: 139
Works, last 5 years: 72
h-index: 40
Scientists listed: 12
Grants since 2016: 829

Grants received

2019–2023 · career development · K99

Mechanisms of Aging: Regulation of Canonical and Non-canonical Autophagy

Jose Luis Nieto-Torres · Discovery Institute · funded by National Institutes of Health

$129.9kAutophagy in Disease and Therapy

2019–2020 · research · R56

Transformative research on the normal and Alzheimer's disease brain through studies of neuronal gene recombination

Jerold Chun · Discovery Institute · funded by National Institutes of Health

$2.4M

2019–2023 · research · R01

MYOD Regulation of 3D Chromatin Structure

Pier Lorenzo Puri · Discovery Institute · funded by National Institutes of Health

$390k

2019–2024 · research · R01

Characterizing the nuclear pore complex-T cell receptor connection

Maximiliano A Dangelo · Discovery Institute · funded by National Institutes of Health

$647.7kNuclear Structure and Function

2019–2023 · research · R01

Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$3 955Pluripotent Stem Cells Research

2019–2022 · research · R01

Ligand functional selectivity in EphA2 receptor signaling

Kalina Hristova · Discovery Institute · funded by National Institutes of Health

$483.6kAxon Guidance and Neuronal Signaling

2019–2024 · research · R01

Denervation activated super-enhancers of pathogenic IL6-STAT3 feedforward loop in FAPs

Pier Lorenzo Puri · Discovery Institute · funded by National Institutes of Health

$429k

2019–2025 · research · R01

Targeting neuroinflammation in AD with novel CX3CR1 agonists

Kevin Ron Nash · Discovery Institute · funded by National Institutes of Health

$554.6k

2019–2021 · career development · K99

Mechanisms of Aging: Regulation of Canonical and Non-canonical Autophagy

Jose Luis Nieto-Torres · Discovery Institute · funded by National Institutes of Health

$129.9kAutophagy in Disease and Therapy

2019–2024 · research · R01

Characterizing the nuclear pore complex-T cell receptor connection

Maximiliano A Dangelo · Discovery Institute · funded by National Institutes of Health

$653.6kNuclear Structure and Function

2019–2021 · research · R21

Transcriptomic and epigenetic regulators of Drosophila heart aging

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$243.8k

2019–2021 · research · R21

Transcriptomic and epigenetic regulators of Drosophila heart aging

Peter D. Adams · Discovery Institute · funded by National Institutes of Health

$292.5k

2019–2023 · research · R01

Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$487.5kPluripotent Stem Cells Research

2019–2022 · research · R61

IGNITE: Development of novel cyclophilin B/PIKfyve inhibitors for treatment of Malignant Peripheral Nerve Sheath Tumors

Richard J Bram · Discovery Institute · funded by National Institutes of Health

$1MSignaling Pathways in Disease

2019–2023 · career development · K99

Mechanisms of Aging: Regulation of Canonical and Non-canonical Autophagy

Jose Luis Nieto-Torres · Discovery Institute · funded by National Institutes of Health

$136.4kAutophagy in Disease and Therapy

2019–2024 · research · R01

Brain pathology and function in a chronic mouse model of ZIKV transmission

Alysson R. Muotri · Discovery Institute · funded by National Institutes of Health

$654.9kMosquito-borne diseases and control

2019–2025 · cooperative agreement · UH3

Development of SBI-553, an allosteric modulator of NTR1, for the treatment of substance use disorders

Lawrence S. Barak · Discovery Institute · funded by National Institutes of Health

$1.3MNeuropeptides and Animal Physiology

2019–2024 · research · R01

Denervation activated super-enhancers of pathogenic IL6-STAT3 feedforward loop in FAPs

Pier Lorenzo Puri · Discovery Institute · funded by National Institutes of Health

$424.7k

2019–2023 · research · R01

The Development of TGR5 Antagonists for the Treatment of Cholangiopathies

Nicholas F. Larusso · Discovery Institute · funded by National Institutes of Health

$537.6kGenetic and Kidney Cyst Diseases

2019–2021 · research · R21

Fbxw7 as a target to promote muscle stem cell expansion

Alessandra Sacco · Discovery Institute · funded by National Institutes of Health

$257.4kMuscle Physiology and Disorders

2019–2020 · research · R21

Cellular Mediators of Cardiac Aging and Arrhythmia in Drosophila

Karen Ocorr · Discovery Institute · funded by National Institutes of Health

$243.8k

2019–2023 · research · R01

Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$532.5kPluripotent Stem Cells Research

2019–2022 · research · R21

Evaluation of a High-Affinity and BTLA-specific HVEM Protein Agonist in vivo

Carl F Ware · Discovery Institute · funded by National Institutes of Health

$243.8k

2019–2022 · fellowship · F32

Role of HDAC7 in senescence-associated inflammation

Karl Nathan Miller · Discovery Institute · funded by National Institutes of Health

$61.6kHistone Deacetylase Inhibitors Research

2019–2023 · research · R01

"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"

Randal J. Kaufman · Discovery Institute · funded by National Institutes of Health

$941.8kEndoplasmic Reticulum Stress and Disease

2019–2023 · research · R01

Discovery of small molecule promoters of cardiomyocyte proliferation to restore cardiac performance in disease

Alexandre Romain Colas · Discovery Institute · funded by National Institutes of Health

$487.5kPluripotent Stem Cells Research

2019–2023 · research · R01

Control of gene expression in neural stem cells by crosstalk between messenger RNA methylation and histone modification

Crystal Zhao · Discovery Institute · funded by National Institutes of Health

$390k

2019–2023 · research · R01

Control of gene expression in neural stem cells by crosstalk between messenger RNA methylation and histone modification

Anindya Bagchi · Discovery Institute · funded by National Institutes of Health

$390k

2019–2024 · research · R01

Targeting neuroinflammation in AD with novel CX3CR1 agonists

Kevin Ron Nash · Discovery Institute · funded by National Institutes of Health

$677.1k

2019–2021 · research · R21

Evaluation of a High-Affinity and BTLA-specific HVEM Protein Agonist in vivo

John R Sedy · Discovery Institute · funded by National Institutes of Health

$292.5k

2019–2021 · research · R21

Nuclear pore regulation of leukemia cell metabolism and survival

Marcela Raices · Discovery Institute · funded by National Institutes of Health

$273.5kNuclear Structure and Function

2019–2024 · research · R01

Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart Failure

Rolf Bodmer · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2019–2021 · grant · S10

Acquisition of a CMOS Imaging Device for the T12 at SBP

Jianhua Zhao · Discovery Institute · funded by National Institutes of Health

$207.3kCCD and CMOS Imaging Sensors

2019–2024 · research · R01

Targeting neuroinflammation in AD with novel CX3CR1 agonists

Kevin Ron Nash · Discovery Institute · funded by National Institutes of Health

$805.3k

2019–2023 · research · R01

Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart Failure

Rolf Bodmer · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2019–2023 · research · R01

MYOD Regulation of 3D Chromatin Structure

Pier Lorenzo Puri · Discovery Institute · funded by National Institutes of Health

$390k

2019–2023 · research · R01

"A Novel Role for the UPR Component, ATF6 in AD-associated Neuroprotective Pathways"

Timothy Yikai Huang · Discovery Institute · funded by National Institutes of Health

$973.4kEndoplasmic Reticulum Stress and Disease

2019–2022 · cooperative agreement · UG3

Development of SBI-553, an allosteric modulator of NTR1, for the treatment of substance use disorders

Lawrence S. Barak · Discovery Institute · funded by National Institutes of Health

$3.6MNeuropeptides and Animal Physiology

2019–2023 · research · R01

Genetic Pathways in Ceramide-Associated Lipotoxic Cardiomyopathy and Heart Failure

Rolf Bodmer · Discovery Institute · funded by National Institutes of Health

$487.5kSphingolipid Metabolism and Signaling

2019–2024 · research · R01

Characterizing the nuclear pore complex-T cell receptor connection

Maximiliano A Dangelo · Discovery Institute · funded by National Institutes of Health

$653.6kNuclear Structure and Function