Beckman Research Institute

2024–2027 · research · Second Century Early Faculty Independence Award

Multi-omics Based Machine Learning to Identify Driving Factors of Heart Failure

Di Ren · Beckman Research Institute · funded by American Heart Association

$300k

2024–2028 · research · R01

The role of bile acid metabolomics in graft-versus-host disease

Justin Cross · Beckman Research Institute · funded by National Institutes of Health

$555.6kGut microbiota and health

2024–2029 · research · R25

Cancer Aging and Metabolism research experience Program (CAMP)

David K. Ann · Beckman Research Institute · funded by National Institutes of Health

$240.9k

2024–2027 · research · R01

Targeting bile acid composition to treat metabolic diseases

Wendong Huang · Beckman Research Institute · funded by National Institutes of Health

$651.4kDrug Transport and Resistance Mechanisms

2024–2025 · fellowship · Postdoctoral Fellowship

Characterization of the cardiac secretome in a genetic mouse model of heart failure through in vivo proximity labeling

Jielin Deng · Beckman Research Institute · funded by American Heart Association

$147.3kBiotin and Related Studies

2024–2026 · research · R21

Non-receptor protein tyrosine phosphatases in macrophage-mediated cancer cell phagocytosis.

Mingye Feng · Beckman Research Institute · funded by National Institutes of Health

$208kProtein Tyrosine Phosphatases

2024–2031 · research · R35

RNA-mediated endotheliopathy in diabetic vasculopathy

Zhen Bouman Chen · Beckman Research Institute · funded by National Institutes of Health

$543.3k

2024–2026 · research · R21

Modulating Intratumoral Immune Composition to Enhance Immunotherapy

Edwin Manuel · Beckman Research Institute · funded by National Institutes of Health

$457.7kCancer Research and Treatments

2024–2029 · research · R01

CMV-specific CD19 CAR T cells amplified in vivo using CMV Triplex vaccine for B-NHL

Ryotaro Nakamura · Beckman Research Institute · funded by National Institutes of Health

$738.7k

2024–2028 · research · R01

Role of autoreactivity in pathogenesis of chronic graft versus host disease

Defu Zeng · Beckman Research Institute · funded by National Institutes of Health

$879.3k

2024–2027 · research · R01

Early Life Exposure to Endocrine Disrupting Chemicals: Epigenomic and Transcriptomic Networks and RAGE in Liver Disease

Ann Marie Schmidt · Beckman Research Institute · funded by National Institutes of Health

$767.7k

2024–2029 · research · R37

The role, mechanism, and therapeutic potential of METTL1 in acute myeloid leukemia

Rui Su · Beckman Research Institute · funded by National Institutes of Health

$434.6k

2024–2027 · research · R01

Targeting bile acid composition to treat metabolic diseases

Wendong Huang · Beckman Research Institute · funded by National Institutes of Health

$599.3k

2024–2031 · research · R35

RNA-mediated endotheliopathy in diabetic vasculopathy

Zhen Bouman Chen · Beckman Research Institute · funded by National Institutes of Health

$813.8k

2024–2029 · research · R01

Quantitative MRI to automatically delineate intraprostatic tumor for radiation therapy

Jia Guo · Beckman Research Institute · funded by National Institutes of Health

$648.8k

2024–2028 · research · R01

The role of bile acid metabolomics in graft-versus-host disease

Philip L Lorenzi · Beckman Research Institute · funded by National Institutes of Health

$585.8k

2024–2029 · research · R50

Leading NCI Clinical Trials Network research nationally and at the City of Hope Comprehensive Cancer Center

Alex F. Herrera · Beckman Research Institute · funded by National Institutes of Health

$208.1k

2024–2029 · program · P01

Administrative, biospecimen and biostatistical core

Robert Jenq · Beckman Research Institute · funded by National Institutes of Health

2023–2028 · research · R01

Exosomal biomarkers for the early detection of hepatocellular carcinoma

Ajay Goel · Beckman Research Institute · funded by National Institutes of Health

$693.1kExtracellular vesicles in disease

2023–2026 · research · Transformational Project Award

Pathogenesis of ischemic heart disease: Converging role of the unfolded protein response and integrated stress response

Zhao Wang · Beckman Research Institute · funded by American Heart Association

$300kEndoplasmic Reticulum Stress and Disease

2023–2028 · research · R01

Exosomal biomarkers for the early detection of hepatocellular carcinoma

Ajay Goel · Beckman Research Institute · funded by National Institutes of Health

$745.3kExtracellular vesicles in disease

2023–2027 · research · R01

Circadian clock and temporal control in nutrient metabolism

Ke Ma · Beckman Research Institute · funded by National Institutes of Health

$435.7kCircadian rhythm and melatonin

2023–2028 · research · R01

Targeting Immune Escape in CML/MPN Transformation

Guido Marcucci · Beckman Research Institute · funded by National Institutes of Health

$571.6kChronic Myeloid Leukemia Treatments

2023–2028 · cooperative agreement · U01

A Prospective Cohort Study of Patients with Non-Small Cell Lung Cancer and Multiple Myeloma to Assess the Benefits and Harms Related to Cannabis Use During Treatment

Jennifer Cullen · Beckman Research Institute · funded by National Institutes of Health

$572.9kCannabis and Cannabinoid Research

2023–2028 · research · R01

Myeloid cell-selective, oligonucleotide-based STAT3 inhibition combined with total marrow and lymphoid irradiation for immunotherapy of acute myeloid leukemia

Susanta K Hui · Beckman Research Institute · funded by National Institutes of Health

$711.3kAcute Myeloid Leukemia Research

2023–2028 · research · R37

Targeting the long isoform of the prolactin receptor to treat autoimmune diseases and B-cell malignancies

Srividya Swaminathan · Beckman Research Institute · funded by National Institutes of Health

$438.2kGrowth Hormone and Insulin-like Growth Factors

2023–2025 · research · R21

Identification of metabolic adducts associated with prostate cancer progression in African American men

Sarah C. Shuck · Beckman Research Institute · funded by National Institutes of Health

$466.5k

2023–2028 · research · R01

Transfer of vaccine-induced immunity from immunocompetent stem cell donor as antiviral immunotherapy to protect high-risk transplant recipients from cytomegalovirus reactivation

Don J Diamond · Beckman Research Institute · funded by National Institutes of Health

$688.1kCytomegalovirus and herpesvirus research

2023–2024 · research · R21

Use of a non-human primate model to define the role of T cell immune responses in persistent Kaposi sarcoma-associated herpesvirus infection and Kaposi sarcoma pathogenesis

Lorraine Zvichapera Mutsvunguma · Beckman Research Institute · funded by National Institutes of Health

$326.5kViral-associated cancers and disorders

2023–2025 · grant · High Impact Pilot Award

Disturbance of NAD Metabolism by Nicotine and E-Cigarette Exposure

Charles Brenner · Beckman Research Institute · funded by Office of the President, University of California

$880k

2023–2025 · research · Innovative Project Award

Secretome of Failing Heart

Zhao Wang · Beckman Research Institute · funded by American Heart Association

$200kBiotin and Related Studies

2023–2027 · research · R01

Pathogenesis, prevention and treatment of corticosteroid-resistant gut GVHD

Defu Zeng · Beckman Research Institute · funded by National Institutes of Health

$839.6kHematopoietic Stem Cell Transplantation

2023–2028 · research · R01

Myeloid cell-selective, oligonucleotide-based STAT3 inhibition combined with total marrow and lymphoid irradiation for immunotherapy of acute myeloid leukemia

Susanta K Hui · Beckman Research Institute · funded by National Institutes of Health

$688kAcute Myeloid Leukemia Research

2023 · grant

Engineering inhibitors of the ERKS axis proteins for glioblastoma treatment

Beckman Research Institute · funded by Uncle Kory Foundation

$50kMelanoma and MAPK Pathways

2023–2028 · research · R01

Define the oncogenic role of METTL3 in the pathogenesis of chronic lymphocytic leukemia

Lili Wang · Beckman Research Institute · funded by National Institutes of Health

$608.9kRNA modifications and cancer

2023

Disturbance of NAD Metabolism by Nicotine and E-Cigarette Exposure

Charles Brenner · Beckman Research Institute · funded by Office of the President, University of California

$880k

2023–2028 · cooperative agreement · U54

1/2 Drug Development and Capacity Building: A UCR/CoH-CCC Partnership

Ernest Martinez · Beckman Research Institute · funded by National Institutes of Health

$1.3M

2023–2028 · research · R01

Advancing Photoacoustic Tomography in breast imaging to predict response in breast cancers treated with neoadjuvant therapy

Lily Lau Lai · Beckman Research Institute · funded by National Institutes of Health

$626kPhotoacoustic and Ultrasonic Imaging

2023–2028 · research · R01

Define the oncogenic role of METTL3 in the pathogenesis of chronic lymphocytic leukemia

Lili Wang · Beckman Research Institute · funded by National Institutes of Health

$556.2kRNA modifications and cancer

2023–2030 · research · R35

The role of the intestinal microbiome in cancer immunotherapy

Marcel R M Van Den Brink · Beckman Research Institute · funded by National Institutes of Health

$1MGut microbiota and health