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Fields · Medicine · Oncology

Drug Transport and Resistance Mechanisms

This cluster of papers explores the mechanisms of multidrug resistance in cancer, focusing on the role of ATP-dependent transporters, P-glycoprotein, bile acids, ABC transporters, and drug efflux pumps. It also delves into the involvement of nuclear receptors, metabolic regulation, and the impact on intestinal barrier function.

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89.7k
Citations
2.3M

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