Fields · Biochemistry, Genetics and Molecular Biology · Aging

Genetics, Aging, and Longevity in Model Organisms

This cluster of papers explores the molecular mechanisms underlying aging, longevity, and age-related diseases. It covers topics such as oxidative stress, genetic regulation of lifespan, the impact of caloric restriction, mitochondrial function, RNA interference, inflammaging, insulin signaling, and proteostasis. The research spans model organisms like C. elegans and Drosophila to mammalian studies, providing insights into the fundamental processes of aging.