Fields · Medicine · Geriatrics and Gerontology

Sirtuins and Resveratrol in Medicine

This cluster of papers explores the role of sirtuins, particularly SIRT1-7, in regulating metabolism, aging, and cellular homeostasis. It investigates the impact of resveratrol, NAD+, calorie restriction, and oxidative stress on sirtuin activity and their implications for longevity and age-related diseases. The cluster also delves into the interplay between sirtuins, mitochondria, and cellular energy balance.