Fields · Biochemistry, Genetics and Molecular Biology · Biotechnology
Cancer Research and Treatments
This cluster of papers focuses on the use of engineered bacteria, particularly Salmonella typhimurium, for targeted cancer therapy. The research involves various strategies such as tumor-specific colonization, gene delivery, immunotherapy, and metabolic manipulation to induce tumor regression and enhance anti-tumor immunity. Fluorescent protein imaging is utilized to visualize tumor growth, metastasis, and angiogenesis in live animals. Additionally, the cluster explores the use of bacterial vectors for gene therapy and the potential of arginine deprivation as a targeted therapy for certain cancers.
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- Works
- 9 846
- Citations
- 154.4k
Scientists whose main topic this is
1Nicholas ArpaiaColumbia University Irving Medical Center · United StatesBiochemistry, Genetics and Molecular Biology2 414citations, 5 yrs42works, 5 yrs30h-index2Tal DaninoColumbia University Irving Medical Center · United StatesBiochemistry, Genetics and Molecular Biology1 946citations, 5 yrs54works, 5 yrs32h-index3Ming Dan ZhaoShanxi Medical University · ChinaBiochemistry, Genetics and Molecular Biology1 590citations, 5 yrs54works, 5 yrs54h-index4Zhenping CaoShanghai Jiao Tong University · ChinaBiochemistry, Genetics and Molecular Biology1 469citations, 5 yrs34works, 5 yrs25h-index5Robert M. HoffmanUniversity of California System · United StatesBiochemistry, Genetics and Molecular Biology1 465citations, 5 yrs185works, 5 yrs104h-index6Candice R. GurbatriTempus Labs (United States) · United StatesBiochemistry, Genetics and Molecular Biology1 121citations, 5 yrs12works, 5 yrs7h-index7Yuying TanWuhan Institute of Technology · ChinaBiochemistry, Genetics and Molecular Biology1 105citations, 5 yrs80works, 5 yrs43h-index8Jongwon ImColumbia University · United StatesBiochemistry, Genetics and Molecular Biology1 060citations, 5 yrs10works, 5 yrs7h-index9Courtney CokerColumbia University Irving Medical Center · United StatesBiochemistry, Genetics and Molecular Biology984citations, 5 yrs17works, 5 yrs15h-index10Jing LiuNanchang University · ChinaBiochemistry, Genetics and Molecular Biology971citations, 5 yrs72works, 5 yrs31h-index11In Young HwangNational University of Singapore · SingaporeBiochemistry, Genetics and Molecular Biology926citations, 5 yrs15works, 5 yrs17h-index12Joanna T. ZhangUniversity of California San Diego · United StatesBiochemistry, Genetics and Molecular Biology760citations, 5 yrs8works, 5 yrs7h-index13Rosa L. VincentBaylor College of Medicine · United StatesBiochemistry, Genetics and Molecular Biology723citations, 5 yrs13works, 5 yrs7h-index14Vadim S. PokrovskyPeoples' Friendship University of Russia · RussiaBiochemistry, Genetics and Molecular Biology721citations, 5 yrs99works, 5 yrs28h-index15Jin Hai ZhengFujian Medical University · ChinaBiochemistry, Genetics and Molecular Biology709citations, 5 yrs44works, 5 yrs24h-index16Jaeseung HahnColumbia University · United StatesBiochemistry, Genetics and Molecular Biology600citations, 5 yrs8works, 5 yrs9h-index17Yeongjin HongChonnam National University · South KoreaBiochemistry, Genetics and Molecular Biology526citations, 5 yrs28works, 5 yrs37h-index18Tetsuhiro HarimotoHarvard University · United StatesBiochemistry, Genetics and Molecular Biology513citations, 5 yrs18works, 5 yrs10h-index19Zhixian Sherrie HuAffiliation unknownBiochemistry, Genetics and Molecular Biology488citations, 5 yrs104works, 5 yrs16h-index20Meghna KomaranchathColumbia University · United StatesBiochemistry, Genetics and Molecular Biology478citations, 5 yrs4works, 5 yrs4h-index