Fields · Chemistry · Organic Chemistry
Synthesis and pharmacology of benzodiazepine derivatives
This cluster of papers focuses on the chemistry, synthesis, and biological evaluation of pyrrolobenzodiazepines, a class of DNA-interactive agents with potent antitumour activity. The research covers topics such as asymmetric synthesis, cross-linking agents, cytotoxicity, and their application in natural product synthesis.
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- Works
- 10.2k
- Citations
- 105.5k
Scientists whose main topic this is
1John Anthony HartleyUniversity College London · United KingdomChemistry3 838citations, 5 yrs144works, 5 yrs75h-index2Khondaker Miraz RahmanKing's College London · United KingdomChemistry766citations, 5 yrs106works, 5 yrs34h-index3Zhizhi ChenKunming University of Science and Technology · ChinaChemistry224citations, 5 yrs30works, 5 yrs18h-index4Heli FanUniversity of Wisconsin–Milwaukee · United StatesChemistry216citations, 5 yrs20works, 5 yrs13h-index5Hanan A. SalahSohag University · EgyptChemistry153citations, 5 yrs9works, 5 yrs10h-index6David E. ThurstonKing's College London · United KingdomChemistry141citations, 5 yrs69works, 5 yrs44h-index7Luke A. MastersonAffiliation unknownChemistry117citations, 5 yrs74works, 5 yrs22h-index8Christopher W. BoyceMerck & Co., Inc., Rahway, NJ, USA (United States) · United StatesChemistry103citations, 5 yrs10works, 5 yrs16h-index9Philip W. HowardAffiliation unknownChemistry96citations, 5 yrs94works, 5 yrs35h-index10Lanzhi WangCentral South University · ChinaChemistry87citations, 5 yrs19works, 5 yrs13h-index11Kazi Sharmin NaharKing's College London · United KingdomChemistry85citations, 5 yrs9works, 5 yrs8h-index12Mark SearceyUniversity of East Anglia · United KingdomChemistry80citations, 5 yrs30works, 5 yrs29h-index13Hui Tao CaiGeorgia Institute of Technology · United StatesChemistry71citations, 5 yrs16works, 5 yrs22h-index14Iryna BotsulaNational University of Pharmacy · UkraineChemistry71citations, 5 yrs11works, 5 yrs4h-index15Federico BrucoliDe Montfort University · United KingdomChemistry55citations, 5 yrs15works, 5 yrs11h-index16Lidija KosychovaVilnius University · LithuaniaChemistry41citations, 5 yrs4works, 5 yrs9h-index17Benny J. EvisonAffiliation unknownChemistry40citations, 5 yrs3works, 5 yrs11h-index18Mark S. TichenorAffiliation unknownChemistry35citations, 5 yrs3works, 5 yrs13h-index19Sabine DepauwUniversité de Strasbourg · FranceChemistry33citations, 5 yrs5works, 5 yrs20h-index20Arnaud C. TiberghienBicycle Therapeutics (United Kingdom) · United KingdomChemistry32citations, 5 yrs45works, 5 yrs19h-index