Fields · Biochemistry, Genetics and Molecular Biology · Cancer Research
Synthesis and Biological Activity
This cluster of papers focuses on the chemistry, biology, and synthesis of antitumor antibiotics, particularly tetrahydroisoquinoline compounds such as Ecteinascidin. It covers topics such as total synthesis, marine-derived compounds, asymmetric synthesis, and DNA binding mechanisms. The research also explores the pharmacological activities and potential clinical utility of these compounds.
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- Works
- 12.8k
- Citations
- 115.1k
Scientists whose main topic this is
1Gerhard BringmannUniversity of Würzburg · GermanyBiochemistry, Genetics and Molecular Biology488citations, 5 yrs76works, 5 yrs75h-index2György DeákUniversity of Debrecen · HungaryBiochemistry, Genetics and Molecular Biology282citations, 5 yrs91works, 5 yrs27h-index3Juan Manuel López‐RomeroUniversidad de Málaga · SpainBiochemistry, Genetics and Molecular Biology181citations, 5 yrs32works, 5 yrs24h-index4Carmen CuevasPharmaMar (Spain) · SpainBiochemistry, Genetics and Molecular Biology145citations, 5 yrs65works, 5 yrs41h-index5George S. HannaMedical University of South Carolina · United StatesBiochemistry, Genetics and Molecular Biology92citations, 5 yrs18works, 5 yrs7h-index6Enrique L. LarghiConsejo Nacional de Investigaciones Científicas y Técnicas · ArgentinaBiochemistry, Genetics and Molecular Biology88citations, 5 yrs22works, 5 yrs20h-index7Federico Moya‐UtreraUniversidad de Málaga · SpainBiochemistry, Genetics and Molecular Biology72citations, 5 yrs13works, 5 yrs4h-index8Hideo KigoshiUniversity of Tsukuba · JapanBiochemistry, Genetics and Molecular Biology72citations, 5 yrs25works, 5 yrs40h-index9Christine T. ChongScripps Research Institute · United StatesBiochemistry, Genetics and Molecular Biology68citations, 5 yrs3works, 5 yrs2h-index10Blaise Kimbadi LombeMax Planck Institute for Chemical Ecology · GermanyBiochemistry, Genetics and Molecular Biology68citations, 5 yrs11works, 5 yrs11h-index11Aleš ŽulaNovartis (Slovenia) · SloveniaBiochemistry, Genetics and Molecular Biology65citations, 5 yrs8works, 5 yrs11h-index12Sherzod Niyatqobulovich ZhurakulovAcademy of Sciences Republic of Uzbekistan · UzbekistanBiochemistry, Genetics and Molecular Biology57citations, 5 yrs54works, 5 yrs7h-index13Amelia DíazUniversidad de Málaga · SpainBiochemistry, Genetics and Molecular Biology56citations, 5 yrs10works, 5 yrs12h-index14Cristina Porras-AlcaláUniversidad de Málaga · SpainBiochemistry, Genetics and Molecular Biology56citations, 5 yrs4works, 5 yrs6h-index15Nuria CabedoUniversitat de València · SpainBiochemistry, Genetics and Molecular Biology55citations, 5 yrs12works, 5 yrs22h-index16Christian GüntherAffiliation unknownBiochemistry, Genetics and Molecular Biology49citations, 5 yrs4works, 5 yrs14h-index17Ali Al‐MourabitCentre National de la Recherche Scientifique · FranceBiochemistry, Genetics and Molecular Biology49citations, 5 yrs27works, 5 yrs38h-index18Saddam HussainLady Reading Hospital · PakistanBiochemistry, Genetics and Molecular Biology45citations, 5 yrs18works, 5 yrs16h-index19Tania TahtouhAbu Dhabi University · United Arab EmiratesBiochemistry, Genetics and Molecular Biology43citations, 5 yrs8works, 5 yrs8h-index20Polina A. SmirnovaFar Eastern Federal University · RussiaBiochemistry, Genetics and Molecular Biology42citations, 5 yrs4works, 5 yrs6h-index