Research funder · United States
Neurofibromatosis Therapeutic Acceleration Program
- Grants since 2016
- 90
- Awarded, last 5 years (where amounts are published)
- 32.6M
- Funded works, last 5 years
- 61
- Funded works, all time
- 118
Grants
2026–2029 · award
Assessment of novel cellular immunotherapies for the treatment of malignant peripheral nerve sheath tumors in advanced 3-dimensional biomimetic models
Kyle Williams · Twin Cities Orthopedics
2026–2029 · award
Understand the molecular mechanisms underlying malignant transformation of NF1-associated nerve sheath tumors
Xiyuan Zhang · Rutgers Sexual and Reproductive Health and Rights
2026–2029 · award
Cerebral cortical mechanisms of sensory hypersensitivity in NF1
John Robinson · Cincinnati Children's Hospital Medical Center
2026–2029 · award
The Role of Microglia in Neurofibromatosis Type 1 Cognitive Phenotypes
Sarah Borrie · Vlaams Instituut voor Biotechnologie
2026–2029 · award
Family-Based Mindfulness in NF1: Enhancing Adolescents’ Emotional Regulation, Social Skills, and Parental Well-Being
Yaffa Serur · Stanford University
2025–2027 · award
Extension of existing Sydney NTAP protocol to include a final healing timepoint for cutaneous neurofibromas
Yemima Berman · Northern Sydney Local Health District
2025–2026 · award
Uncovering the molecular landscape of cutaneous neurofibromas
Sheila Mansouri · Mayo Clinic
2025–2026 · award
Restoring neurofibromin function in cutaneous and plexiform neurofibroma and MPNST
Lu Le · University of Virginia
2025–2028 · award
Addendum #7: NF-OSI Data Coordination and Platform Services
Robert Allaway · Sage Bionetworks
2024 · award
Liquid biopsy with ctDNA to detect minimal residual disease after MPNST resection in neurofibromatosis patients
Jordina Rincon Torroella · Johns Hopkins University
2024–2027 · award
Assessment of Tumor-Related Disfigurement and Appearance Concerns in Neurofibromatosis Type 1
Vanessa Merker · Massachusetts General Hospital
2024–2027 · award
A Phase 1/2a Open-label, Multicenter Dose Finding Study to Evaluate the Safety and Anti-Tumor Activity of Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)
Carlos Romo · University of Virginia
2024–2027 · award
A multidimensional approach to understanding and treating sleep disorders in children and adolescents with neurofibromatosis Type 1
Natalie Pride · Sydney Children’s Hospitals Network
2023–2026 · award
New targets for the treatment of cutaneous neurofibromas
Alison Lloyd · University College London
2023–2027 · award
Combining the inhibition of the Ras/MAPK pathway and the activation of the cAMP/PKA pathway as a therapeutic strategy for cutaneous neurofibroma
Eduard Serra-Arenas · Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2023–2024 · award
Uncovering the molecular landscape of cutaneous neurofibromas
Sheila Mansouri
2023–2026 · award
Assessment of Tumor-Related Disfigurement and Appearance Concerns in Neurofibromatosis Type 1
Staci Martin Peron · National Cancer Institute
2023–2025 · award
Development of paired NF1-MPNST-PDX-cell lines for Precision Medicine Efforts
Angela Hirbe · Washington University in St. Louis
2023–2025 · award
Is RasL11A a mechanism for cutaneous neurofibromas regression?
Katherine Gurdziel · Wayne State University
2023–2026 · award
Exploring the role of cutaneous innervation in the initiation and development of cNFs in neurofibromatosis type 1
Piotr Topilko · Paris-Est Sup
2023–2025 · award
Leveraging patient-derived cutaneous neurofibroma organoid models to identify biomarkers of drug response
Alice Soragni · Pacific Northwest National Laboratory
2023–2026 · award
Targeting the stem-like cells in Plexiform Neurofibromas
Daochun Sun · Medical College of Wisconsin
2023–2027 · award
A Whole Animal Approach For Developing A Novel cNF Therapeutic Lead
Ross Cagan · Medical Research Council
2023–2026 · award
Novel Treatments for Cutaneous Neurofibroma
Richard Anderson · Massachusetts General Hospital
2023–2028 · award
Investigating the clinical impact of cutaneous neurofibromas in a large clinical and photographic database
Kavita Sarin · The Board Of Trustees Of The Leland Stanford Junior University
2023–2027 · award
Standardizing the analysis of cutaneous neurofibromas in Nf1-KO mice and exploring drugs targeting tumor cells and their microenvironment in this model
Laura Fertitta · Hôpitaux Universitaires Henri-Mondor
2023–2025 · award
Optical Detection of Nascent cNF and Development of a Laser Treatment Strategy
Thomas Milner · University of California, Irvine
2023–2027 · award
Combining the inhibition of the Ras/MAPK pathway and the activation of the cAMP/PKA pathway as a therapeutic strategy for cutaneous neurofibroma
Piotr Topilko · Paris-Est Sup
2023–2027 · award
Optimizing outcomes for children and adults with neurofibromatosis-associated tumors
Chelsea Kotch · Children's Hospital of Philadelphia
2022–2023 · award
Exploiting ERK-dependence with combination targeted therapy in NF1-/- glioma
Karisa Schreck · Johns Hopkins University
2022–2024 · award
Untargeted Lipidomics in Human Cutaneous Neurofibroma Samples
Jaishri Blakeley · Johns Hopkins University
2022–2025 · award
Understanding how epigenetic dysregulation and Ras misactivation cooperate during NF1 deficient Schwann cell tumorigenesis
Harish Vasudevan · Regent University
2022–2025 · award
Multi-omic liquid biopsy analysis for early detection of malignant transformation of peripheral nerve sheath tumors in patients with neurofibromatosis type 1 (NF1)
Russell Sundby · Center for Cancer Research
2022–2026 · award
NTAP-SAGE: NF Data Portal, Bioinformatics Support, Sage Research Projects
Robert Allaway · Sage Bionetworks
2022 · award
Early treatment of cutaneous neurofibromas type 1 (cNF) to markedly improve patient's quality of life
Thomas Milner · University of California, Irvine
2022–2024 · award
High-Intensity Focused Ultrasound (HIFU), a novel method for treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1: Safety and Efficacy
Jorgen Serup · Bispebjerg Hospital
2022–2023 · award
Restoring neurofibromin function in cutaneous neurofibroma
Lu Le · University of Virginia
2021–2027 · award
The Johns Hopkins NF1 biospecimen repository
Christine Pratilas · Johns Hopkins University
2021–2023 · award
Evaluation of Standard Treatment Outcomes for Cutaneous Neurofibromas in People with NF1: An International Pilot study
Yemima Berman · The University of Sydney
2021–2023 · award
Evaluation of Standard Treatment Outcomes for Cutaneous Neurofibromas in People with NF1: An International Pilot study
Pierre Wolkenstein · Université Paris-Est Créteil
