Research funder · United States
Neurofibromatosis Therapeutic Acceleration Program
- Grants since 2016
- 90
- Awarded, last 5 years (where amounts are published)
- 32.6M
- Funded works, last 5 years
- 61
- Funded works, all time
- 118
Grants
2021–2024 · award
Tolerability of device-based therapies for Neurofibromatosis Type 1 cutaneous neurofibromas
Richard Anderson · Massachusetts General Hospital
2021–2024 · award
Human induced pluripotent stem cell modeling of sensory neuron-regulated NF1-deficient Schwann cell growth
David Gutmann · Washington University in St. Louis
2021–2028 · award
Multi-parametric Imaging Biomarker Development to Predict Malignant Conversion in Patients with Neurofibromatosis Type 1
Shivani Ahlawat · Johns Hopkins University
2021–2026 · award
NTAP NF1 Gene Replacement Initiative: Development of a gene replacement therapy for cutaneous neurofibromas related to NF1
Verena Staedtke · Johns Hopkins University
2021–2023 · award
Evaluating genetic modifiers of cutaneous neurofibromas in adults with neurofibromatosisi Type 1
Kavita Sarin · The Board Of Trustees Of The Leland Stanford Junior University
2021–2022 · award
Identifying markers of response and resistance to experimental therapies for neurofibromas
Michael Fisher · Children's Hospital of Philadelphia
2021–2026 · award
Towards clinical translation of imaging studies in Neurofibromatosis type 1
Tamar Green · The Board Of Trustees Of The Leland Stanford Junior University
2021–2022 · award
Uncovering the molecular alterations that drive malignant transformation in NF1- associated peripheral nerve sheath tumors
Suganth Suppiah · University Health Network
2021–2027 · award
Natural history study of cutaneous neurofibromas in people with NF1
Carlos Romo
2021–2026 · award
Defining the factors that dictate the pattern of glioma formation in NF1
Nicole Brossier · Washington University in St. Louis
2021–2023 · award
The impact of phenotype/germline NF1 variant on radiographic response of plexiform neurofibroma to mitogen-activated protein kinase (MEK) inhibition
Chelsea Kotch · Children's Hospital of Philadelphia
2020–2021 · award
Cell type specificity of NF1 binding partners and effects of variants with divergent genotype phenotype correlations
Deeann Wallis · University of Alabama at Birmingham
2020–2021 · award
Developing ELISA/IHC-Capable NF1 Monoclonal Antibody
Michelle Mattson-Hoss · Infixion Bioscience, Inc.
2020–2024 · award
Targeting the Let7-HMGA2 axis in Malignant Peripheral Nerve Sheath Tumor Prevention
Steven Rhodes · Indiana University
2020–2021 · award
Therapeutic targetig of the immunosuppresive microenvironment in MPNSTs
Rebecca Dodd · University of Iowa
2019–2020 · award
Evaluation of CP-137401 in Plexiform Neurofibroma using a Pre-clinical Mouse Model of Neurofibromatosis Type 1
D. Wade Clapp
2018–2019 · award
Evaluation of Erk1/2, CDK4/6, and PI3K Inhibition in Plexiform Neurofibromas Utilizing a Murine Pre-Clinical Model of Neurofibromatosis type 1
D. Wade Clapp
2018–2022 · award
Modeling cNF with human schwann cells via tunable and reversible contol of NF1 proten
Gabsang Lee · Johns Hopkins University
2018–2021 · award
Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors
Juha Peltonen · University of Turku
2018–2022 · award
NTAP-SAGE: Management of Data, Website Development and Community Engagement, Generation of New Data, Hypotheses and Analyses
Robert Allaway · Sage Bionetworks
2018–2021 · award
Identification of pathways triggered by Schwann cell-fibroblast interactions driving cutaneous neurofibroma growth
Eduard Serra-Arenas · Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2018–2022 · award
Genetic Studies of Neurofibromatosis
Margaret Wallace · University of Florida
2018–2022 · award
Imaging predictors of malignant peripheral nerve sheath tumors
Kien-Ninh Ly · Masschusetts General Hospital
2018–2022 · award
Deconstrution and reconstitution of NF1 cutaneous neurofibromas
Ray Mattingly · Wayne State University
2018–2021 · award
Pilot Study of Factors Impacting Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
Staci Peron · National Cancer Institute
2018–2021 · award
Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies
Piotr Topilko · Paris-Est Sup
2018–2023 · award
The role of GABA in the working memory impairment in Neurofibromatosis Type 1
Shruti Garg · University of Manchester
2018–2021 · award
Cutaneous Neurofibroma: Models, Biology and Translation
2018–9999 · award
ATCC Reimbursement
Jaishri Blakeley · Johns Hopkins University
2018–2021 · award
A 3D Cutaneous Neurofibroma Model for Automated High-throughput Drug Screenings
Alice Soragni · The Regents Of The University Of California, Los Angeles
2018–2023 · award
Imaging Biomarkers of Neurofibromatosis Type 1-Associated Optic Pathway Glioma
Peter De Blank · Cincinnati Children's Hospital Medical Center
2018–2021 · award
Leveraging human iPSCs to determine the impact of patient-derived NF1 gene mutations on peripheral sensory neuron-driven Schwann cell growth
David Gutmann · Washington University in St. Louis
2017–2018 · award
Search of the molecular mechanisms sustaining plexiform neurofibroma formation in a novel three-dimensional in vitro model
Federica Chiara · University of Padua
2017–2019 · award
TRAPping the metabolic adaptations of plexiform neurofibroma
Giorgio Colombo · Institute of Chemistry of Molecular Recognition
2017–2020 · award
TRAPping the metabolic adaptations of plexiform neurofibroma
Andrea Rasola · University of Padua
2017–2021 · award
Novel therapeutic development of NF1-associated malignant peripheral nerve sheath tumor (MPNST)
Ping Chi · Memorial Sloan Kettering Cancer Center
2017–2021 · award
A Nerve Sheath Tumor Bank from Patients with Neurofibromatosis Type 1 (NF1)
Christine Pratilas · Johns Hopkins University
2017–2022 · award
Development of a Preclinical NF1-MPNST Platform Suitable for Precision Oncology Drug Discovery and Evaluation
Angela Hirbe · Washington University in St. Louis
2017–2021 · award
High-Resolution Ultrasonography and Optical Frequency Domain Imaging for Measurement and Characterization of Cutaneous Neurofibromas in Patients with NF1
Scott Plotkin · Massachusetts General Hospital
2017–2018 · award
Combinatorial use of immunotherapeurtics with C. novyi-NT for the treatment of NF1-associated MPNSTs
Verena Staedtke · Johns Hopkins University