Institut de Génétique Humaine

2026 · research · AAPG2025

Interplay between DNA TOPology and 3D GENome ORganisation

Armelle Lengronne · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€635.8k

2026 · research · AAPG2025

Impact of mitochondria and the actin network on germ granule functional organization.

Anne Ramat · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€320.5k

2026 · grant · T-ERC

Revisiting Translation: Real-Time Single-Molecule Dynamics of RNA-Binding Proteins in Live Cells

Sora Yang · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€116k

2026 · research · AAPG2025

Molecular and biophysical insights into translation at germ granules

Martine Simonelig · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€487.3kRNA Research and Splicing

2025 · research · AAPG2025

Define metabolic vulnerabilities in Multiple Myeloma

Jerome Moreaux · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€591.8kMultiple Myeloma Research and Treatments

2025 · research · AAPG2025

Down-regulate RAD51 to succeed in meiotic recombination?

Frédéric Baudat · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€653.4kDNA Repair Mechanisms

2025 · research · AAPG2025

Linking meiotic double strand break formation to chromosome pairing

Corinne Grey · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€590.7kDNA Repair Mechanisms

2025–2028 · award

Epigenetic homeostasis as oncogenic barrier during cell differentiation

Cristina Fracassi · Institut de Génétique Humaine · funded by Human Frontier Science Program

2024 · grant · T-ERC

Nuclear pores in higher-order chromatin organization

Charlene Boumendil · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€113.5kNuclear Structure and Function

2023 · research · AAPG2023

Replication Stress caused by Post-replicative RNA:DNA hybrids

Philippe Pasero · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€682kDNA Repair Mechanisms

2023 · research · AAPG2023

Deciphering the role of the heterochromatin mark H3K9me3 in mammalian testicular determination

Francis Poulat · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€786.1k

2023 · research · AAPG2023

Crosstalk between epitranscriptomic and epigenetic mechanisms in gene regulation during B to plasma cell differentiation

Jerome Moreaux · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€736.3kRNA modifications and cancer

2023 · research · AAPG2023

Assembly of macromolecular complexes by HSP90/R2TP

Edouard Bertrand · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€740.3kHeat shock proteins research

2023 · research · AAPG2023

Study the genomic instability of embryonic stem cells

Domenico Maiorano · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€594.8kPluripotent Stem Cells Research

2022 · research · AAPG2021

Biophysical mechanism and functional consequences of TopBP1 condensation

Jihane Basbous · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€518.3k

2022 · research · AAPG2021

Interaction between PKA signalling and TRIM28 in ovarian maintenance and pathology

Francis Poulat · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€739.6kGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

2022 · research · AAPG2021

The role of tubulin detyrosination in the acquisition of neuronal polarity.

Krzysztof Rogowski · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€639.2kMicrotubule and mitosis dynamics

2022 · research · AAPG2021

Linking nuclear pores to chromatin organization and senescence

Charlène Boumendil · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€287.7k

2022 · research · AAPG2021

EJC impact on mRNA localization and packaging

Edouard Bertrand · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€616.6k

2022 · research · AAPG2021

Uncovering the rules and mechanism of target-directed microRNA degradation

Hervé Seitz · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€497.5k

2021 · research · AAPG2020

Functions of condensin: from a structural role to the control of genomic stability

Armelle Lengronne · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€584.8kDNA Repair Mechanisms

2021–2024 · award

The fate of functional chromatin states through mitosis: a single-cell analysis

Flora Paldi · Institut de Génétique Humaine · funded by Human Frontier Science Program

Genomics and Chromatin Dynamics

2020 · research · AAPG2019

Transposopathies of p53-less flies

Severine Chambeyron · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€484k

2020 · grant · Montage de Réseaux Scientifiques Européens et/ou Internationaux

Building a European Training and Research network using Innovative technologies to harness innate immune responses

Nadine Laguette · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€30kinterferon and immune responses

2019 · grant · E-Rare-3

Identification of converging Molecular Pathways Across Chromatinopathies as Targets for Therapy

Giacomo Cavalli · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€250k

2019 · research · AAPG2018

Reconstitution of the meiotic DNA double strand break complex and activity in vitro

Bernard De Massy · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€445kCancer therapeutics and mechanisms

2019 · research · AAPG2019

RNA:DNA hybrids and replication fork instability

Philippe Pasero · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€614.2kDNA Repair Mechanisms

2018 · research · AAPG2018

Role of three-dimensional chromatin organization and spatial co-localization during B to plasma cell differentiation

Jerome Moreaux · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€508.7k

2018 · research · AAPG2017

Determinants of replisome progression in presence of obstacles

Cyril Ribeyre · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€301.7k

2018 · research · AAPG2017

Ribosomal and small non-coding RNAs in oculopharyngeal muscular dystrophy

Martine Simonelig · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€352.9kGenetic Neurodegenerative Diseases

2017 · research · AAPG2016

Investigating widespread regulation of gene expression through intron retention

Fernandez-Luco Reini · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€269.2kRNA Research and Splicing

2017 · research · AAPG2016

AN INTEGRATED ROLE FOR CHROMATIN AND lncRNAs IN DEFINING CELL-SPECIFIC SPLICING PROGRAMS

Fernandez-Luco Reini · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€314.5kRNA Research and Splicing

2017 · research · AAPG2016

Interplays between Genome Maintenance and Pervasive Transcription

Philippe Pasero · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€390.9k

2016 · research · AAPG2016

Role of TRIM28 in maintenance of ovarian identity and primary sex-determination

Francis Poulat · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€584.1k

2016 · research · AAPG2016

Small RNA-directed heterochromatin establishment

Kazufumi Mochizuki · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€600k

2016 · research · AAPG2015

Molecular aspects of mRNA regulation by piRNAs and RNA binding proteins in Drosophila

Martine Simonelig · Institut de Génétique Humaine · funded by Agence Nationale de la Recherche

€290.5kRNA Research and Splicing