Discipline
News, research analysis and evidence-based explanation. 20 stories in this section.
A new experimental drug that disables the antioxidant defense PRX3 controlled disease progression in 67% of mesothelioma patients in an early clinical trial, offering hope for a cancer with few …
A global analysis of medical research has found that women with the same heart, kidney, liver, and neurological conditions as men are significantly less likely to be offered interventions such …
Digital wearables are increasingly used to collect continuous patient data in clinical research, yet questions persist about whether the devices meet the standards of scientific evidence and whether they can …
Stanford researchers implanted human cerebral organoids into mice engineered to lack over 90 percent of their cortex, restoring maze-learning and motor function and creating a model that may improve study …
A University of Chicago radiology professor and the 2025 PMB Early Career Award winner discuss breakthroughs in advanced X-ray imaging, the ingredients of high-impact research, and strategies for early-career scientists …
A University of Georgia team has developed an improved light-sheet microscope that captures fast 3D images of seizures in zebrafish, finding that seizures originate in the hindbrain and propagate forward, …
A new study in Nature Medicine reports that an autonomous clinical AI agent deployed on-premise achieved high diagnostic accuracy and selective autonomy, offering a reliable path for AI-assisted medical decisions …
A large review of surveys and long-term studies finds that regular reading for enjoyment is associated with stronger brain structure, improved mental health and lower risk of cognitive decline, even …
A new brain-computer interface decodes speech and gestures at the same time in two people with paralysis, enabling more natural communication through an avatar.
A one-of-a-kind microscope named Curie, operating at ten times the resolution of conventional instruments, is giving researchers new hope of understanding inflammatory bowel disease and finding treatments for the growing …
Researchers have identified a previously overlooked layer of Alzheimer's disease: the three-dimensional organization of DNA inside brain cells is disrupted, changing how genes are switched on and off.
Researchers report that a natural compound found in spinach, almonds, and sweet potatoes may aggravate gut inflammation in people with Crohn's disease and ulcerative colitis because their intestines process oxalate …
A new study shows that combining multiple patient-level biomarkers can better predict which cancer patients will respond to immunotherapy, though generalizability remains a challenge.
Preclinical research shows that targeting the IL1RAP protein can disrupt an inflammatory network that shields pancreatic tumors, reducing fibrosis and suppressor cells while enhancing T cell activity — a strategy …
As gene-editing treatments move from trials to clinics, experts emphasize the need for rigorous safety monitoring and equitable patient access.
The randomized phase 2 ImmunoPRISM trial found that teclistamab produced more complete clinical responses than lenalidomide-dexamethasone in patients with high-risk smoldering multiple myeloma, though longer follow-up is needed to confirm …
A new Lancet perspective argues that medicine's dominant narratives about race and ethnicity are overwhelmingly negative, and that biomedical research must move beyond stigmatizing labels like «hard to reach» to …
A Lancet commentary examines whether the rVSVΔG-ZEBOV-GP vaccine's induced seroreactivity offers real protection against Bundibugyo virus, which has caused 5,815 confirmed cases and 2,788 deaths in the Democratic Republic of …
Researchers have demonstrated for the first time that human heart muscle cells can regenerate after a heart attack, overturning the long-held view that damage to the heart is permanent and …
A detailed case study of Maria Branyas, who lived past 117, reveals that extreme longevity may combine advanced aging with low inflammation, beneficial gut bacteria, protective genetics, and a biological …
