Discipline
News, research analysis and evidence-based explanation. 20 stories in this section.
A new study suggests that age-related brain shrinkage may not follow a steady decline but instead pause during the transition to menopause, potentially reshaping how researchers understand neurological aging in …
The International Consortium of Digital Twins in Healthcare and Medicine has been established to develop medical digital twin technology as a new infrastructure for precision health, according to a new …
Nature Medicine has published an author correction to the SCREESCO randomized controlled trial, which compared colonoscopy and fecal immunochemical testing with usual care in diagnostic colorectal cancer screening.
A new vision-based pathology foundation model, CRISP, has been developed exclusively from frozen section slides to support treatment decisions during surgery, with validation including a prospective cohort.
A nationwide cohort study finds that COVID-19 mRNA vaccination before or after starting immune checkpoint inhibitors was associated with modest improvements in overall survival, mostly in the first few months, …
A study found that AP503 activates the GPR133 receptor, boosting bone formation and slowing bone loss in mice, with potential implications for osteoporosis and age-related muscle decline.
Scientists are engineering bacteria to manufacture and deliver anticancer drugs directly to tumors, potentially reducing chemotherapy side effects. The approach is still in early testing, with more animal and human …
As clinical trial data on women’s health continues to lag, researchers argue that real-world data and citizen science offer a practical path to better evidence and improved care.
Bursts of pink noise timed to slow brainwaves during sleep appear to increase cerebrospinal fluid flow, potentially enhancing the brain's waste-disposal system, according to a small study.
A preclinical study reveals a potential combination therapy that targets prostate cancers that evade treatment by changing their cellular identity, slowing tumor growth.
Two separate child deaths linked to experimental genetic interventions have intensified debate over the safeguards, transparency and oversight of investigator-initiated trials in China.
A mouse model shows that Oropouche virus can spread through developing embryos, with pronounced brain infection and abnormalities including microcephaly, strengthening concern about infection during pregnancy.
Researchers isolated monoclonal antibodies that can interfere with alpha-gal-specific IgE binding and suppress basophil activation, offering a possible route toward a targeted treatment for red-meat allergy.
Gut bacterial composition explained more variation in most measured inflammatory markers than chronological age and was associated with future disease risk, but the study does not prove causation.
Experiments link pathological tau to mitochondrial complex I and reverse electron transport, creating a cycle of oxidative stress that may offer a new target in tau-related neurodegeneration.
Two doses of psilocybin before chemotherapy prevented peripheral nerve injury and pain-related changes in mice, pointing to an unexpected neuroprotective research direction beyond psychiatry.
Starting semaglutide late in life increased median lifespan in female mice by about 12% and improved several measures of cognition, metabolism and molecular aging.
Daraxonrasib produced objective responses in roughly one-third of patients with previously treated RAS-mutant non-small-cell lung cancer, while serious adverse events remained frequent.
Early clinical data from CTX310 show that a single CRISPR-Cas9 treatment aimed at ANGPTL3 can produce sustained reductions in LDL cholesterol and triglycerides for at least 12 months.
A 16-patient study generated CD19 CAR-T cells inside the body with a lentiviral vector, producing deep B-cell depletion and early clinical improvement without the usual ex vivo manufacturing step.
